Viewing posts tagged liver
After yesterday's good news that James's bone marrow has been given the all clear, we had an appointment with the Prof who is in charge of James's treatment where we were able to hear more fully about the bone marrow test and analysis. We appreciated that both Prof and James's pediatrician seem to understand how difficult this is for parents emotionally!
After last week's liver troubles there's been a lot of emotional up and down - waiting to hear whether James could still have the Methotrexate, and pondering the consequences of stopping it (with a risk of relapse) or the potential damage to his liver of continuing it.
Last week James started feeling a bit nauseous around food again, and so we asked them to test his liver condition. (This is after his liver apparently recovering from his two episodes last year). The results showed that his liver is struggling again - this time, only one of the four tests was abnormal, but it was 10 times the normal level. This was apparently a fairly clear indication of drug-related liver problems, and so we were told to not give James his weekly Methotrexate this week and then to test again. Today he was tested and the level that was high has dropped significantly, which seems to strongly indicate that his liver is not handling the Methotrexate.
It's been a month of refocusing and recovery...
This last few weeks it's felt as though emotions ranging from joys to griefs have been running hand in hand...
It's been quite a week in the Fraser household, featuring James's liver issues, David going to Joburg for the day on Wednesday and Charis being taken for a precautionary blood test to make sure she doesn't have leukemia!
We went to see the gastro-enterologist today as planned to check out why James's liver enzyme levels were high. He said that the most likely reason is that some of the drugs he's on can gradually produce toxicity in the liver over protracted periods of time. This can eventually produce liver scarring etc which is not reversible, but if caught early enough, they can sometimes switch the drugs etc so that it doesn't have a permanent effect.
Over the last month James has been feeling nauseous a fair amount (he hasn't really struggled with this over the previous few months) - often retching at the sight of food and/or not wanting to eat, which has been quite stretching... it's been a little bit better the last week but still there. On Thursday they did some blood tests on him and his liver enzyme levels were quite high, which could be a cause, so tomorrow we're taking him to see a gastroenterologist about it (they told us not to worry or panic! Nice reassuring people, these medical folks are :-))